Dichloromethane → Tert-butyl 3-(cyclopropanecarbonylamino)pyrrolidine-1-carboxylate

HRID 289375Notes

Reaction equation

HRID 289375 reaction equation
[CH3:44][CH2:45][N:46]([CH2:47][CH3:48])[CH2:49][CH3:50].[Cl:51][CH2:52][Cl:53].[NH2:1][CH:2]1[CH2:3][N:4]([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:5][CH2:6]1.[OH:14][C:15](=[O:16])[CH:17]1[CH2:18][CH2:19]1.[P-:20]([F:21])([F:22])([F:23])([F:24])([F:25])[F:26].[n:27]1([O:28][C:29]([N:30]([CH3:31])[CH3:32])=[N+:33]([CH3:34])[CH3:35])[c:36]2[n:37][cH:38][cH:39][cH:40][c:41]2[n:42][n:43]1>>[NH:1]([CH:2]1[CH2:3][N:4]([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:5][CH2:6]1)[C:15](=[O:14])[CH:17]1[CH2:18][CH2:19]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 9886HexafluorophosphateHCID 15655Cyclopropanecarboxylic acidHCID 27563701-Boc-3-aminopyrrolidineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium

Product 1

HCID 67098401Tert-butyl 3-(cyclopropanecarbonylamino)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-a1ed231c9d03477597440490842e625d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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