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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 289458Generated: October 29, 2026

Methanol → 4-(5-chloro-6-(2,2,2-trifluoroethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)tetrahydro-2H-pyran-4-carboxylic acid

https://huagongshe.com/reaction/289458

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantHCID 57995665HCID 57995665—
Product4-(5-chloro-6-(2,2,2-trifluoroethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)tetrahydro-2H-pyran-4-carboxylic acidHCID 57995569—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-4a57c261a7ff4316826c6995f078bfa7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)