m-Chloroperbenzoic acid → HCID 178526236, compound

HRID 28946Notes

Reaction equation

HRID 28946 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[NH:8][CH:9]=[CH:10][C:3]=12.ClC1C=CC=C(C(OO)=[O:19])C=1>C(OCC)C>[Br:1][C:2]1[CH:7]=[CH:6][N+:5]([O-:19])=[C:4]2[NH:8][CH:9]=[CH:10][C:3]=12

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 222736434-Bromo-1H-pyrrolo[2,3-b]pyridine

Product 1

HCID 178526236HCID 178526236, compoundYield 87%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a solution of 4-bromo-1H-pyrrolo[2,3-b]pyridine (25 mmol) in diethyl ether (400 mL) under nitrogen at room temperature was added m-chloroperbenzoic acid (40 mmol). The reaction was stirred for 2.5 h. The resultant precipitate was filtered and washed with cold ether (50 mL) to give the title compound as an off-white solid (87%). ESMS[M+H]+: 213.2

Workup

  1. filtrationThe resultant precipitate was filtered
  2. washwashed with cold ether (50 mL)

Sources & evidence

ORD record
ord-77492fc20e8b4276b1167027ea9afd3b
Source dataset
uspto-grants-2008_09
Patent number
US07419988B2

Reaction notes

Loading…