N-methyl-2-pyrrolidone → 2-Isopropyl-5-methyl-cyclohexanecarboxylic acid [2-(2-cyano-phenyl)-ethyl]-amide

HRID 289627Notes

Reaction equation

HRID 289627 reaction equation
[Br:1][c:2]1[c:3]([CH2:8][CH2:9][NH:10][C:11](=[O:12])[CH:13]2[CH:14]([CH:20]([CH3:21])[CH3:22])[CH2:15][CH2:16][CH:17]([CH3:19])[CH2:18]2)[cH:4][cH:5][cH:6][cH:7]1.[CH3:26][N:27]1[CH2:28][CH2:29][CH2:30][C:31]1=[O:32].[Cu:23][C:24]#[N:25]>>[c:2]1([C:24]#[N:25])[c:3]([CH2:8][CH2:9][NH:10][C:11](=[O:12])[CH:13]2[CH:14]([CH:20]([CH3:21])[CH3:22])[CH2:15][CH2:16][CH:17]([CH3:19])[CH2:18]2)[cH:4][cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 13387N-methyl-2-pyrrolidoneHCID 668315152-Isopropyl-5-methyl-cyclohexanecarboylic acid [2-(2-bromo-phenyl)-ethyl]-amideHCID 178418546HCID 178418546, compound

Product 1

HCID 668315242-Isopropyl-5-methyl-cyclohexanecarboxylic acid [2-(2-cyano-phenyl)-ethyl]-amide

Sources & evidence

ORD record
ord-40928902aa7546b494200527b280e4fc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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