Sodium ion → tert-butyl N-[1-[3-(2,3-dihydro-1-benzofuran-5-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrrolidin-3-yl]carbamate

HRID 289663Notes

Reaction equation

HRID 289663 reaction equation
[Br:16][c:17]1[cH:18][n:19][c:20]2[c:21]([n:22]1)[n:23]([CH2:26][c:27]1[cH:28][cH:29][c:30]3[c:31]([cH:35]1)[CH2:32][CH2:33][O:34]3)[n:24][n:25]2.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][NH:10][CH2:11][CH2:12]1)=[O:13].[H-:15].[Na+:14].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41].[OH2:36]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][N:10]([c:17]2[cH:18][n:19][c:20]3[c:21]([n:22]2)[n:23]([CH2:26][c:27]2[cH:28][cH:29][c:30]4[c:31]([cH:35]2)[CH2:32][CH2:33][O:34]4)[n:24][n:25]3)[CH2:11][CH2:12]1)=[O:13]

Participants

7

Reactant 6

HCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 166653HydrideHCID 2757234tert-butyl N-(pyrrolidin-3-yl)carbamateHCID 593418446-bromo-1-(2,3-dihydro-benzofuran-5-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazine

Product 1

HCID 67458658tert-butyl N-[1-[3-(2,3-dihydro-1-benzofuran-5-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrrolidin-3-yl]carbamate

Sources & evidence

ORD record
ord-592e764781a04c5892f557410ae958c6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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