HRID290109

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

2 次

HCID85318

(Pyridin-2-yl)acetic acid

C7H7NO2

HCID87677864

3-Benzhydryl-4-[[3,5-bis(trifluoromethyl)phenyl]methoxy]piperidine

C27H25F6NO

PRODUCTS

产物

HCID87676885

1-[3-Benzhydryl-4-[[3,5-bis(trifluoromethyl)phenyl]methoxy]piperidin-1-yl]-2-pyridin-2-ylethanone

C34H30F6N2O2

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-1b6dcc70e54044b299646d6023f26833
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (8/10)

反应SMILES

[CH:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[CH:15]1[CH2:16][NH:17][CH2:18][CH2:19][CH:20]1[O:21][CH2:22][c:23]1[cH:24][c:25]([C:33]([F:34])([F:35])[F:36])[cH:26][c:27]([C:29]([F:30])([F:31])[F:32])[cH:28]1.[ClH:1].[ClH:37].[n:38]1[c:39]([CH2:44][C:45](=[O:46])[OH:47])[cH:40][cH:41][cH:42][cH:43]1>>[CH:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[CH:15]1[CH2:16][N:17]([C:45]([CH2:44][c:39]2[n:38][cH:43][cH:42][cH:41][cH:40]2)=[O:46])[CH2:18][CH2:19][CH:20]1[O:21][CH2:22][c:23]1[cH:24][c:25]([C:33]([F:34])([F:35])[F:36])[cH:26][c:27]([C:29]([F:30])([F:31])[F:32])[cH:28]1