Toluene → 2-(4-cyclopropylpiperazin-1-yl)-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]pyrimidine-5-carboxamide
Reaction equation
[CH3:1][Al:2]([CH3:3])[CH3:4].[CH3:42][c:43]1[cH:44][cH:45][cH:46][cH:47][cH:48]1.[CH3:5][O:6][c:7]1[cH:8][c:9]([CH2:15][CH2:16][c:17]2[cH:18][c:19]([NH2:22])[nH:20][n:21]2)[cH:10][c:11]([O:13][CH3:14])[cH:12]1.[CH:23]1([N:26]2[CH2:27][CH2:28][N:29]([c:32]3[n:33][cH:34][c:35]([C:38](=[O:39])[O:40][CH3:41])[cH:36][n:37]3)[CH2:30][CH2:31]2)[CH2:24][CH2:25]1>>[CH3:5][O:6][c:7]1[cH:8][c:9]([CH2:15][CH2:16][c:17]2[cH:18][c:19]([NH:22][C:38]([c:35]3[cH:34][n:33][c:32]([N:29]4[CH2:28][CH2:27][N:26]([CH:23]5[CH2:24][CH2:25]5)[CH2:31][CH2:30]4)[n:37][cH:36]3)=[O:39])[nH:20][n:21]2)[cH:10][c:11]([O:13][CH3:14])[cH:12]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0e250d67e0a84cedb57b02535010d2ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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