Borane → Tert-butyl 4-(1-hydroxypropan-2-yl)piperazine-1-carboxylate

HRID 290334Notes

Reaction equation

HRID 290334 reaction equation
[BH3:6].[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12](=[O:13])[N:14]1[CH2:15][CH2:16][N:17]([CH:20]([C:21](=[O:22])[OH:23])[CH3:24])[CH2:18][CH2:19]1.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[O:1]1[CH2:2][CH2:3][CH2:4][CH2:5]1>>[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12](=[O:13])[N:14]1[CH2:15][CH2:16][N:17]([CH:20]([CH2:21][OH:22])[CH3:24])[CH2:18][CH2:19]1

Participants

4

Reactant 3

HCID 6331BoraneHCID 8028Tetrahydrofuran2×HCID 27356452-(4-(tert-Butoxycarbonyl)piperazin-1-yl)propanoic acid

Product 1

HCID 50987509Tert-butyl 4-(1-hydroxypropan-2-yl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-b07affd675c0466a812517090d0fe1be
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…