Hydrochloric Acid → 3'-(4-fluoro-phenyl)-4-[3-(1-methyl-1H-pyrazol-4-yl)-propyl]-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl
Reaction equation
[Br:30][CH2:31][CH2:32][CH2:33][c:34]1[cH:35][n:36][n:37]([CH3:39])[cH:38]1.[C:22](=[O:23])([O-:24])[O-:25].[CH3:40][C:41]#[N:42].[ClH:1].[ClH:2].[F:3][c:4]1[cH:5][cH:6][c:7](-[c:10]2[c:11]([N:16]3[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]3)[n:12][cH:13][cH:14][n:15]2)[cH:8][cH:9]1.[I-:29].[K+:26].[K+:27].[K+:28]>>[F:3][c:4]1[cH:5][cH:6][c:7](-[c:10]2[c:11]([N:16]3[CH2:17][CH2:18][N:19]([CH2:31][CH2:32][CH2:33][c:34]4[cH:35][n:36][n:37]([CH3:39])[cH:38]4)[CH2:20][CH2:21]3)[n:12][cH:13][cH:14][n:15]2)[cH:8][cH:9]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-503fc29170074feb910caa8b254ae255
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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