Acetone → 1-[1-(4-Chlorophenyl)cyclobutyl]-3-hydroxy-3-methylbutan-1-one oxime
Reaction equation
[CH3:21][C:22]([CH3:23])=[O:24].[CH3:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31].[Cl:6][c:7]1[cH:8][cH:9][c:10]([C:13]2([C:17]([CH3:18])=[N:19][OH:20])[CH2:14][CH2:15][CH2:16]2)[cH:11][cH:12]1.[Li:1][CH2:2][CH2:3][CH2:4][CH3:5].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[OH2:25]>>[Cl:6][c:7]1[cH:8][cH:9][c:10]([C:13]2([C:17]([CH2:18][C:22]([CH3:21])([CH3:23])[OH:24])=[N:19][OH:20])[CH2:14][CH2:15][CH2:16]2)[cH:11][cH:12]1Participants
7
Sources & evidence
- ORD record
- ord-bb124585d27b4d27950647cd55d52c54
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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