2-Bromobenzonitrile → 2-[4-Hydroxy-1-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]benzonitrile
Reaction equation
[Br:21][c:22]1[c:23]([C:24]#[N:25])[cH:26][cH:27][cH:28][cH:29]1.[F:1][C:2]([c:3]1[n:4][n:5][c:6]2[n:7]1[n:8][c:9]([N:12]1[CH2:13][CH2:14][C:15](=[O:18])[CH2:16][CH2:17]1)[cH:10][cH:11]2)([F:19])[F:20]>>[F:1][C:2]([c:3]1[n:4][n:5][c:6]2[n:7]1[n:8][c:9]([N:12]1[CH2:13][CH2:14][C:15]([OH:18])([c:22]3[c:23]([C:24]#[N:25])[cH:26][cH:27][cH:28][cH:29]3)[CH2:16][CH2:17]1)[cH:10][cH:11]2)([F:19])[F:20]Participants
3
Sources & evidence
- ORD record
- ord-42d5248348a94437b6240b5a6e697573
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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