Diethyl Ether → 4-Methylpiperazine-1-carboxylic acid {4-[2-fluoro-4-(3-phenylacetylureido)phenoxy]pyridin-2-yl}amide
Reaction equation
[CH3:38][CH2:39][O:40][CH2:41][CH3:42].[F:48][c:49]1[cH:50][c:51]([NH:52][C:53]([NH:54][C:55](=[O:56])[CH2:57][c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)=[S:64])[cH:65][cH:66][c:67]1[O:68][c:69]1[n:70][cH:71][n:72][c:73]([NH:74][C:75]([N:76]2[CH2:77][CH2:78][CH2:79][CH2:80]2)=[O:81])[cH:82]1.[NH2:1][c:2]1[cH:3][c:4]([F:25])[c:5]([O:6][c:7]2[cH:8][c:9]([NH:13][C:14](=[O:15])[N:16]3[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]3)[n:10][cH:11][cH:12]2)[cH:23][cH:24]1.[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1.[c:26]1([CH2:32][C:33](=[O:34])[N:35]=[C:36]=[O:37])[cH:27][cH:28][cH:29][cH:30][cH:31]1>>[NH:1]([c:2]1[cH:3][c:4]([F:25])[c:5]([O:6][c:7]2[cH:8][c:9]([NH:13][C:14](=[O:15])[N:16]3[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]3)[n:10][cH:11][cH:12]2)[cH:23][cH:24]1)[C:36]([NH:35][C:33]([CH2:32][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)=[O:34])=[O:37]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-33845026033b4bed96af04a0b6d661f9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…