Triethylamine → 2-Bromo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-3-methoxythiophene-4-carboxamide
Reaction equation
[Br:1][c:2]1[s:3][cH:4][c:5]([C:9](=[O:10])[OH:11])[c:6]1[O:7][CH3:8].[CH3:12][CH2:13][N:14]([CH2:15][CH3:16])[CH2:17][CH3:18].[CH3:19][O:20][c:21]1[c:22]([N:28]2[CH2:29][CH2:30][N:31]([CH3:34])[CH2:32][CH2:33]2)[cH:23][c:24]([NH2:27])[cH:25][cH:26]1.[S:35]([Cl:36])([Cl:37])=[O:38]>>[Br:1][c:2]1[s:3][cH:4][c:5]([C:9](=[O:11])[NH:27][c:24]2[cH:23][c:22]([N:28]3[CH2:29][CH2:30][N:31]([CH3:34])[CH2:32][CH2:33]3)[c:21]([O:20][CH3:19])[cH:26][cH:25]2)[c:6]1[O:7][CH3:8]Participants
5
Sources & evidence
- ORD record
- ord-33eb9419252643fdbdaec0abe3e7e71d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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