反应详情

温度

190 °C

A mixture of N-[2,3,6-trimethyl-4-[[2-methyl-3-(4-methylphenyl)-2-propenyl]oxy]phenyl]formamide (920 g), potassium carbonate (4.6 g) and N,N-dimethylaniline (2760 ml) was stirred at 190° C. for 4 hr under nitrogen stream. The mixture was cooled to 100° C. and heptane (1840 ml) was added dropwise thereto. The mixture was further cooled to 30° C. and heptane (3680 ml) was added dropwise thereto. The mixture was stirred at the same temperature for 1 hr, and the precipitated crystals were collected by filtration and washed with heptane to give the title compound (799.5 g, yield 86.9%).

1. temperatureThe mixture was cooled to 100° C.
2. temperatureThe mixture was further cooled to 30° C.
3. stirringThe mixture was stirred at the same temperature for 1 hr
4. filtrationthe precipitated crystals were collected by filtration
5. washwashed with heptane