Dimethyl Sulfoxide → Tert-butyl 2-((2-chloro-4-sulfamoylphenylamino)methyl)morpholine-4-carboxylate

HRID 291230Notes

Reaction equation

HRID 291230 reaction equation
[CH2:28]([N:29]([CH:30]([CH3:31])[CH3:32])[CH:33]([CH3:34])[CH3:35])[CH3:36].[CH3:37][S:38]([CH3:39])=[O:40].[Cl:1][c:2]1[cH:3][c:4]([S:9](=[O:10])(=[O:11])[NH2:12])[cH:5][cH:6][c:7]1[F:8].[NH2:13][CH2:14][CH:15]1[O:16][CH2:17][CH2:18][N:19]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:20]1>>[Cl:1][c:2]1[cH:3][c:4]([S:9](=[O:10])(=[O:11])[NH2:12])[cH:5][cH:6][c:7]1[NH:13][CH2:14][CH:15]1[O:16][CH2:17][CH2:18][N:19]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:20]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 81531DiisopropylethylamineHCID 75098833-Chloro-4-fluorobenzenesulfonamideHCID 19081094tert-Butyl 2-(aminomethyl)morpholine-4-carboxylate

Product 1

HCID 67126756Tert-butyl 2-((2-chloro-4-sulfamoylphenylamino)methyl)morpholine-4-carboxylate

Sources & evidence

ORD record
ord-b60cf46cdb904ef8b7d5d520a0de67a5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…