Acetic Acid → 2-(4-Fluorophenyl)-7-(1-methylpiperidin-4-yl)-3-(pyrimidin-4-yl)imidazo[1,2-a]pyridine

HRID 291296Notes

Reaction equation

HRID 291296 reaction equation
[C:32]([BH3-:33])#[N:34].[CH2:29]=[O:30].[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[CH3:36][OH:37].[CH3:43][C:44](=[O:45])[OH:46].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([cH:12][cH:13][c:14]([CH:16]4[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]4)[cH:15]3)[c:22]2-[c:23]2[n:24][cH:25][n:26][cH:27][cH:28]2)[cH:6][cH:7]1.[Na+:35].[OH2:31]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([cH:12][cH:13][c:14]([CH:16]4[CH2:17][CH2:18][N:19]([CH3:32])[CH2:20][CH2:21]4)[cH:15]3)[c:22]2-[c:23]2[n:24][cH:25][n:26][cH:27][cH:28]2)[cH:6][cH:7]1

Participants

9

Reactant 8

HCID 176Acetic AcidHCID 712FormaldehydeHCID 887MethanolHCID 923Sodium ionHCID 962WaterHCID 8028TetrahydrofuranHCID 498716Cyano-borohydrideHCID 692084082-(4-Fluorophenyl)-3-(pyrimidin-4-yl)-7-piperidin-4-ylimidazo[1,2-a]pyridine

Product 1

HCID 111651142-(4-Fluorophenyl)-7-(1-methylpiperidin-4-yl)-3-(pyrimidin-4-yl)imidazo[1,2-a]pyridine

Sources & evidence

ORD record
ord-fb43cc7b9de14ee686d9af58b284d015
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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