Dichloromethane → 1-[2-(4-Aminopiperidin-1-yl)ethyl]-2-oxo-1,2-dihydroquinoline-7-carbonitrile

HRID 291362Notes

Reaction equation

HRID 291362 reaction equation
[C:1]([N:5]([C:2](=[O:3])[O-:4])[CH:9]1[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][n:17]2[c:18](=[O:29])[cH:19][cH:20][c:21]3[cH:22][cH:23][c:24]([C:27]#[N:28])[cH:25][c:26]23)[CH2:13][CH2:14]1)([CH3:6])([CH3:7])[CH3:8].[Cl:37][CH2:38][Cl:39].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[NH2:5][CH:9]1[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][n:17]2[c:18](=[O:29])[cH:19][cH:20][c:21]3[cH:22][cH:23][c:24]([C:27]#[N:28])[cH:25][c:26]23)[CH2:13][CH2:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 178449649HCID 178449649, compound

Product 1

HCID 602009201-[2-(4-Aminopiperidin-1-yl)ethyl]-2-oxo-1,2-dihydroquinoline-7-carbonitrile

Sources & evidence

ORD record
ord-aa737dc0b1f24b7086479c8f74af379c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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