Methanol → 5-[4-(5-Fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentylamino]quinoline-2-carboxylic acid methyl ester
Reaction equation
[BH4-:36].[C:38]([O:39][CH2:40][CH3:41])(=[O:42])[CH3:43].[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]2[cH:8][cH:9][cH:10][c:11]([N:15]=[CH:16][C:17]([CH2:18][C:19]([CH3:20])([CH3:21])[c:22]3[c:23]([O:29][CH3:30])[cH:24][cH:25][c:26]([F:28])[cH:27]3)([C:31]([F:32])([F:33])[F:34])[OH:35])[c:12]2[cH:13][cH:14]1.[CH3:44][CH2:45][CH2:46][CH2:47][CH2:48][CH3:49].[CH3:50][OH:51].[Na+:37]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]2[cH:8][cH:9][cH:10][c:11]([NH:15][CH2:16][C:17]([CH2:18][C:19]([CH3:20])([CH3:21])[c:22]3[c:23]([O:29][CH3:30])[cH:24][cH:25][c:26]([F:28])[cH:27]3)([C:31]([F:32])([F:33])[F:34])[OH:35])[c:12]2[cH:13][cH:14]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-a0e0afd373404affb6e8e62d0a5a8c9d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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