2-(Methylamino)ethanol → trans-(4-{4-[(2-Hydroxy-ethyl)-methyl-amino]-butoxymethyl}-cyclohexylmethyl)-methyl-carbamic acid 4-chloro-phenyl ester

HRID 291591Notes

Reaction equation

HRID 291591 reaction equation
[CH3:32][N:33]([CH3:34])[C:35](=[O:36])[CH3:37].[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:8][C:9]([N:10]([CH3:11])[CH2:12][CH:13]2[CH2:14][CH2:15][CH:16]([CH2:19][O:20][CH2:21][CH2:22][CH2:23][CH2:24][Br:25])[CH2:17][CH2:18]2)=[O:26])[cH:6][cH:7]1.[OH:27][CH2:28][CH2:29][NH:30][CH3:31]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:8][C:9]([N:10]([CH3:11])[CH2:12][CH:13]2[CH2:14][CH2:15][CH:16]([CH2:19][O:20][CH2:21][CH2:22][CH2:23][CH2:24][N:30]([CH2:29][CH2:28][OH:27])[CH3:31])[CH2:17][CH2:18]2)=[O:26])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 80162-(Methylamino)ethanolHCID 31374DimethylacetamideHCID 69638504HCID 69638504, compound

Product 1

HCID 69638464trans-(4-{4-[(2-Hydroxy-ethyl)-methyl-amino]-butoxymethyl}-cyclohexylmethyl)-methyl-carbamic acid 4-chloro-phenyl ester

Sources & evidence

ORD record
ord-46632c40466f458bb6cd44946a2b622b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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