Hydrochloric Acid → Hydrochloric Acid

HRID 291642Notes

Reaction equation

HRID 291642 reaction equation
[CH3:36][OH:37].[ClH:35].[F:3][c:4]1[c:5]([NH:6][c:7]2[n:8][cH:9][n:10][c:11]3[cH:12][c:13]([NH:19][C:20]([CH2:21][O:22][CH3:23])=[O:24])[c:14]([O:17][CH3:18])[cH:15][c:16]23)[cH:25][c:26]([O:30][C:31]([O:32][CH3:33])=[O:34])[c:27]([CH3:29])[cH:28]1.[Na+:2].[OH-:1].[OH2:38]>>[ClH:35].[F:3][c:4]1[c:5]([NH:6][c:7]2[n:8][cH:9][n:10][c:11]3[cH:12][c:13]([NH:19][C:20]([CH2:21][O:22][CH3:23])=[O:24])[c:14]([O:17][CH3:18])[cH:15][c:16]23)[cH:25][c:26]([OH:30])[c:27]([CH3:29])[cH:28]1

Participants

8

Reactant 6

HCID 313Hydrochloric AcidHCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 107894254-(2-Fluoro-5-methoxycarbonyloxy-4-methylanilino)-6-methoxy-7-methoxyacetamidoquinazoline

Product 2

HCID 313Hydrochloric AcidHCID 5329031Anilinoquinazoline deriv. 33

Sources & evidence

ORD record
ord-c2a255d21ade4763b6ad67fa5099ccf6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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