Sodium ion → 4-(4-Chloro-2-fluoro-5-hydroxy-phenylamino)-6-methoxy-7-(2-morpholin-4-yl-ethoxy)-quinoline-3-carbonitrile
Reaction equation
[CH2:29]1[CH2:30][O:31][CH2:32][CH2:33][NH:34]1.[CH3:37][O:38][CH2:39][CH2:40][O:41][CH3:42].[Cl:1][c:2]1[cH:3][c:4]([F:28])[c:5]([NH:9][c:10]2[c:11]([C:26]#[N:27])[cH:12][n:13][c:14]3[cH:15][c:16]([O:22][CH2:23][CH2:24][Cl:25])[c:17]([O:20][CH3:21])[cH:18][c:19]23)[cH:6][c:7]1[OH:8].[I-:36].[Na+:35]>>[Cl:1][c:2]1[cH:3][c:4]([F:28])[c:5]([NH:9][c:10]2[c:11]([C:26]#[N:27])[cH:12][n:13][c:14]3[cH:15][c:16]([O:22][CH2:23][CH2:24][N:34]4[CH2:29][CH2:30][O:31][CH2:32][CH2:33]4)[c:17]([O:20][CH3:21])[cH:18][c:19]23)[cH:6][c:7]1[OH:8]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-748f888c39e14a009577acd9137cb183
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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