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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 291710Generated: October 25, 2026

Sodium ion → 4-(4-Chloro-2-fluoro-5-hydroxy-phenylamino)-6-methoxy-7-(2-morpholin-4-yl-ethoxy)-quinoline-3-carbonitrile

https://huagongshe.com/reaction/291710

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantMorpholineHCID 8083—
ReactantIodide IonHCID 30165—
Reactant4-(4-Chloro-2-fluoro-5-hydroxy-phenylamino)-7-(2-chloro-ethoxy)-6-methoxy-quinoline-3-carbonitrileHCID 22466748—
Product4-(4-Chloro-2-fluoro-5-hydroxy-phenylamino)-6-methoxy-7-(2-morpholin-4-yl-ethoxy)-quinoline-3-carbonitrileHCID 22466637—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-748f888c39e14a009577acd9137cb183
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)