Hydrochloric Acid → 4-[4-(4-Chlorophenyl)-1,4-diazepan-1-yl]pyrrolidin-3-ol

HRID 291976Notes

Reaction equation

HRID 291976 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([N:14]2[CH2:15][CH2:16][N:17]([c:21]3[cH:22][cH:23][c:24]([Cl:27])[cH:25][cH:26]3)[CH2:18][CH2:19][CH2:20]2)[CH:11]([OH:13])[CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[CH2:35]([Cl:36])[Cl:37].[ClH:28].[O:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1>>[NH:8]1[CH2:9][CH:10]([N:14]2[CH2:15][CH2:16][N:17]([c:21]3[cH:22][cH:23][c:24]([Cl:27])[cH:25][cH:26]3)[CH2:18][CH2:19][CH2:20]2)[CH:11]([OH:13])[CH2:12]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 66967969Tert-butyl 3-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-4-hydroxypyrrolidine-1-carboxylate

Product 1

HCID 669684954-[4-(4-Chlorophenyl)-1,4-diazepan-1-yl]pyrrolidin-3-ol

Sources & evidence

ORD record
ord-31ab1e7a9283454ebace73c27ef8e95f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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