Diethyl Ether → [4-Amino-2-(1-[3-[3-hydroxy-1-(2-hydroxy-ethyl)-propylamino]-propane-1-sulfonyl]-piperidin-4-ylamino)-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanone
Reaction equation
[Al+3:43].[CH3:48][CH2:49][O:50][CH2:51][CH3:52].[H-:42].[H-:45].[H-:46].[H-:47].[Li+:44].[NH2:1][c:2]1[n:3][c:4]([NH:20][CH:21]2[CH2:22][CH2:23][N:24]([S:27](=[O:28])(=[O:29])[CH2:30][CH2:31][CH2:32][Cl:33])[CH2:25][CH2:26]2)[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([F:19])[c:12]([F:18])[cH:13][cH:14][c:15]1[O:16][CH3:17].[NH2:34][CH:35]([CH2:36][CH2:37][OH:38])[CH2:39][CH2:40][OH:41]>>[NH2:1][c:2]1[n:3][c:4]([NH:20][CH:21]2[CH2:22][CH2:23][N:24]([S:27](=[O:28])(=[O:29])[CH2:30][CH2:31][CH2:32][NH:34][CH:35]([CH2:36][CH2:37][OH:38])[CH2:39][CH2:40][OH:41])[CH2:25][CH2:26]2)[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([F:19])[c:12]([F:18])[cH:13][cH:14][c:15]1[O:16][CH3:17]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-2f5e25a0b9ba42ed81655a3a39126911
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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