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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 292295Generated: October 26, 2026

Toluene → 1-cyclobutyl-3-[4-[4-(3-methylmorpholin-4-yl)-7-pyrimidin-2-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

https://huagongshe.com/reaction/292295

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantPhosgeneHCID 6371—
ReactantTriethylamineHCID 8471—
Reactant1,4-DioxaneHCID 31275—
ReactantCyclobutylamineHCID 75645—
Reactant4-[4-(3-methylmorpholin-4-yl)-7-pyrimidin-2-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]anilineHCID 67176516—
Product1-cyclobutyl-3-[4-[4-(3-methylmorpholin-4-yl)-7-pyrimidin-2-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]ureaHCID 67177229—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-225dfcd9b06f4ae6b5166c8414099c74
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)