Toluene → 1-cyclobutyl-3-[4-[4-(3-methylmorpholin-4-yl)-7-pyrimidin-2-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
Reaction equation
[CH2:31]1[CH2:35][O:34][CH2:33][CH2:32][O:36]1.[CH3:1][CH:2]1[CH2:3][O:4][CH2:5][CH2:6][N:7]1[c:8]1[c:9]2[c:10]([n:11][c:12](-[c:14]3[cH:15][cH:16][c:17]([NH2:18])[cH:19][cH:20]3)[n:13]1)[CH2:21][N:22]([c:25]1[n:26][cH:27][cH:28][cH:29][n:30]1)[CH2:23][CH2:24]2.[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[CH3:53][c:54]1[cH:55][cH:56][cH:57][cH:58][cH:59]1.[Cl:44][C:45](=[O:46])[Cl:47].[NH2:48][CH:49]1[CH2:50][CH2:51][CH2:52]1>>[CH3:1][CH:2]1[CH2:3][O:4][CH2:5][CH2:6][N:7]1[c:8]1[c:9]2[c:10]([n:11][c:12](-[c:14]3[cH:15][cH:16][c:17]([NH:18][C:31](=[O:36])[NH:48][CH:49]4[CH2:50][CH2:51][CH2:52]4)[cH:19][cH:20]3)[n:13]1)[CH2:21][N:22]([c:25]1[n:26][cH:27][cH:28][cH:29][n:30]1)[CH2:23][CH2:24]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-225dfcd9b06f4ae6b5166c8414099c74
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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