Ethyl Acetate → 5-amino-2-tert-butyl-1H-indole-4-carbonitrile

HRID 292569Notes

Reaction equation

HRID 292569 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[nH:6][c:7]2[cH:8][cH:9][c:10]([N+:16]([O-:17])=[O:18])[c:11]([C:14]#[N:15])[c:12]2[cH:13]1.[CH3:19][CH2:20][O:21][C:22]([CH3:23])=[O:24]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[nH:6][c:7]2[cH:8][cH:9][c:10]([NH2:16])[c:11]([C:14]#[N:15])[c:12]2[cH:13]1

Participants

3

Reactant 2

HCID 8857Ethyl AcetateHCID 591295222-tert-butyl-5-nitro-1H-indole-4-carbonitrile

Product 1

HCID 591295115-amino-2-tert-butyl-1H-indole-4-carbonitrile

Sources & evidence

ORD record
ord-d85e21f45eb64bcfafe4d85d6cfd6d75
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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