Trifluoroacetic acid → 5-(4-Amino-3-cyclohex-1-enyl-phenyl)-1,3-dimethyl-tetrahydro-pyrimidin-2-one

HRID 292927Notes

Reaction equation

HRID 292927 reaction equation
[C:25]1([B:31]([OH:32])[OH:33])=[CH:26][CH2:27][CH2:28][CH2:29][CH2:30]1.[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[NH2:8][c:9]1[c:10]([Br:24])[cH:11][c:12]([CH:15]2[CH2:16][N:17]([CH3:23])[C:18](=[O:22])[N:19]([CH3:21])[CH2:20]2)[cH:13][cH:14]1>>[NH2:8][c:9]1[c:10]([C:25]2=[CH:26][CH2:27][CH2:28][CH2:29][CH2:30]2)[cH:11][c:12]([CH:15]2[CH2:16][N:17]([CH3:23])[C:18](=[O:22])[N:19]([CH3:21])[CH2:20]2)[cH:13][cH:14]1

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 38629021-Cyclohexenylboronic acidHCID 597712585-(4-Amino-3-bromophenyl)-1,3-dimethyl-1,3-diazinan-2-one

Product 1

HCID 597712595-(4-Amino-3-cyclohex-1-enyl-phenyl)-1,3-dimethyl-tetrahydro-pyrimidin-2-one

Sources & evidence

ORD record
ord-4c43c0dd54f64721b4c69c6acbad11b2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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