Ethylenediamine → 8-(2,6-Difluoro-3,5-dimethoxy-phenyl)-quinoxaline-5-carbonitrile

HRID 292982Notes

Reaction equation

HRID 292982 reaction equation
[Br:1][c:2]1[c:3]2[n:4][cH:5][cH:6][n:7][c:8]2[c:9](-[c:12]2[c:13]([F:23])[c:14]([O:21][CH3:22])[cH:15][c:16]([O:19][CH3:20])[c:17]2[F:18])[cH:10][cH:11]1.[CH3:27][N:28]1[CH2:29][CH2:30][CH2:31][C:32]1=[O:33].[Cu:24][C:25]#[N:26].[NH2:34][CH2:35][CH2:36][NH2:37]>>[c:2]1([C:25]#[N:26])[c:3]2[n:4][cH:5][cH:6][n:7][c:8]2[c:9](-[c:12]2[c:13]([F:23])[c:14]([O:21][CH3:22])[cH:15][c:16]([O:19][CH3:20])[c:17]2[F:18])[cH:10][cH:11]1

Participants

5

Reactant 4

HCID 3301EthylenediamineHCID 13387N-methyl-2-pyrrolidoneHCID 59292933HCID 59292933, compoundHCID 178418546HCID 178418546, compound

Product 1

HCID 592928748-(2,6-Difluoro-3,5-dimethoxy-phenyl)-quinoxaline-5-carbonitrile

Sources & evidence

ORD record
ord-86b78d716ac04e67bb756eb6b1777a8b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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