Hydrogen Bromide → 3-Amino-1-isobutyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

HRID 293005Notes

Reaction equation

HRID 293005 reaction equation
[BrH:34].[CH2:1]([O:2][C:3](=[O:4])[NH:11][CH:12]1[C:13](=[O:33])[N:14]([CH2:29][CH:30]([CH3:31])[CH3:32])[c:15]2[c:16]([cH:25][cH:26][cH:27][cH:28]2)[C:17]([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)=[N:18]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1.[CH2:35]([Cl:36])[Cl:37]>>[NH2:11][CH:12]1[C:13](=[O:33])[N:14]([CH2:29][CH:30]([CH3:31])[CH3:32])[c:15]2[c:16]([cH:25][cH:26][cH:27][cH:28]2)[C:17]([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)=[N:18]1

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 6344DichloromethaneHCID 184442513-Benzyloxycarbonylamino-1-isobutyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Product 1

HCID 197568673-Amino-1-isobutyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Sources & evidence

ORD record
ord-65b38c8f160149c989d9cbfa7ba280f5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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