Dichloromethane → 1-(4-Pyridylpiperidin-4-ylcarbonyl)piperazine

HRID 293012Notes

Reaction equation

HRID 293012 reaction equation
[C:1]([O:2][N:6]1[CH2:7][CH2:8][N:9]([C:12](=[O:13])[CH:14]2[CH2:15][CH2:16][N:17]([c:20]3[cH:21][cH:22][n:23][cH:24][cH:25]3)[CH2:18][CH2:19]2)[CH2:10][CH2:11]1)([CH3:3])([CH3:4])[CH3:5].[Cl:33][CH2:34][Cl:35].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[NH:6]1[CH2:7][CH2:8][N:9]([C:12](=[O:13])[CH:14]2[CH2:15][CH2:16][N:17]([c:20]3[cH:21][cH:22][n:23][cH:24][cH:25]3)[CH2:18][CH2:19]2)[CH2:10][CH2:11]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 187002554-(t-Butoxy)-1-(4-pyridylpiperidin-4-ylcarbonyl)piperazine

Product 1

HCID 108022941-(4-Pyridylpiperidin-4-ylcarbonyl)piperazine

Sources & evidence

ORD record
ord-7d60aac542224ea08b038ab9859315cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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