Bicarbonate Ion → 4-Fluoro-4-(methylsulfonyloxymethyl)-1-piperidinecarboxylic acid tert-butyl ester
Reaction equation
[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[CH3:24][S:25]([Cl:26])(=[O:27])=[O:28].[Cl:34][CH2:35][Cl:36].[F:1][C:2]1([CH2:15][OH:16])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1.[Na+:33].[O-:29][C:30]([OH:31])=[O:32]>>[F:1][C:2]1([CH2:15][O:16][S:25]([CH3:24])(=[O:27])=[O:28])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-7593fcedd53a4375b67d6f53550c354f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…