HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopropane → HCID 68715227, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopropane | HCID 6358 | — |
| Reactant | Ethyl 3-methyl-4-hydroxy-5-ethylbenzofuran-2-carboxylate | HCID 68711669 | — |
| Product | HCID 68715227 | HCID 68715227 | 89.7% |
Reaction Steps
According to the procedure of Example 86, Step 3 0.200 g (0.81 mmol) of 3-methyl-4-hydroxy-5-ethylbenzofuran carboxylic acid ethyl ester (Example 86, Step 2) and 0.379 mL (4.03 mmol) of 2-bromopropane gave 0.211 g of 5-ethyl-4-isopropoxy-3-methylbenzofuran-2-carboxylic acid ethyl ester after chromatography on silica gel eluting with ethyl acetate/hexanes (1:20).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07420001B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-028d37f88a364b38bbb8410a0bcb7819 |
| Source note | uspto-grants-2008_09 |