Methane → 1-[5-chloro-3-[5-(5-hydroxypentyl)-2-methoxyphenyl]-1-[4-methoxy-2-(trifluoromethoxy)phenyl]sulfonyl-2-oxoindol-3-yl]-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
Reaction equation
[C:55].[CH3:53][OH:54].[Cl:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([S:11](=[O:12])(=[O:13])[c:14]1[c:15]([O:22][C:23]([F:24])([F:25])[F:26])[cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]1)[C:6](=[O:27])[C:5]2([c:28]1[c:29]([O:40][CH3:41])[cH:30][cH:31][c:32]([CH2:34][CH:35]=[CH:36][CH2:37][CH2:38][OH:39])[cH:33]1)[N:42]1[CH:43]([C:44](=[O:45])[N:46]([CH3:47])[CH3:48])[CH2:49][CH:50]([OH:52])[CH2:51]1.[Pd:56]>>[Cl:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([S:11](=[O:12])(=[O:13])[c:14]1[c:15]([O:22][C:23]([F:24])([F:25])[F:26])[cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]1)[C:6](=[O:27])[C:5]2([c:28]1[c:29]([O:40][CH3:41])[cH:30][cH:31][c:32]([CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][OH:39])[cH:33]1)[N:42]1[CH:43]([C:44](=[O:45])[N:46]([CH3:47])[CH3:48])[CH2:49][CH:50]([OH:52])[CH2:51]1Participants
5
Sources & evidence
- ORD record
- ord-7b0ac1b8f3734f2085506c6fa686ebbb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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