Dimethyl Sulfoxide → Amifloxacin

HRID 293871Notes

Reaction equation

HRID 293871 reaction equation
[B:26]([OH:27])([F:28])[F:29].[CH3:1][N:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1.[CH3:30][S:31](=[O:32])[CH3:33].[F:8][c:9]1[cH:10][c:11]2[c:12](=[O:25])[c:13]([C:22](=[O:23])[OH:24])[cH:14][n:15]([NH:20][CH3:21])[c:16]2[cH:17][c:18]1[Cl:19]>>[B:26]([OH:27])([F:28])[F:29].[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([c:18]2[c:9]([F:8])[cH:10][c:11]3[c:12](=[O:25])[c:13]([C:22](=[O:23])[OH:24])[cH:14][n:15]([NH:20][CH3:21])[c:16]3[cH:17]2)[CH2:6][CH2:7]1

Participants

6

Reactant 4

HCID 679Dimethyl SulfoxideHCID 531671-MethylpiperazineHCID 139635DifluorohydroxyboraneHCID 30212917-Chloro-6-fluoro-1,4-dihydro-1-(methylamino)-4-oxoquinoline-3-carboxylic acid

Product 2

HCID 55492AmifloxacinHCID 139635Difluorohydroxyborane

Sources & evidence

ORD record
ord-47872e7717aa47938d410f7b3d367e93
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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