Dichloromethane → N-[2-[(2,3-Difluorobenzyl)thio]-6-(3-hydroxypropoxy)pyrimidin-4-yl]piperazine-1-sulfonamide
Reaction equation
[Cl:46][CH2:47][Cl:48].[F:1][c:2]1[c:3]([CH2:4][S:5][c:6]2[n:7][c:8]([O:29][CH2:30][CH2:31][CH2:32][OH:33])[cH:9][c:10]([NH:12][S:13](=[O:14])(=[O:15])[N:16]3[CH2:17][CH2:18][N:19]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:20][CH2:21]3)[n:11]2)[cH:34][cH:35][cH:36][c:37]1[F:38].[F:39][C:40]([F:41])([F:42])[C:43]([OH:44])=[O:45]>>[F:1][c:2]1[c:3]([CH2:4][S:5][c:6]2[n:7][c:8]([O:29][CH2:30][CH2:31][CH2:32][OH:33])[cH:9][c:10]([NH:12][S:13](=[O:14])(=[O:15])[N:16]3[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]3)[n:11]2)[cH:34][cH:35][cH:36][c:37]1[F:38]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-505506eaee984968b742e034beddd96d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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