Tetrahydrofuran → 2-[5-(6-Chloro-2-methylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]ethanol

HRID 294010Notes

Reaction equation

HRID 294010 reaction equation
[C:1]([Si:2]([c:3]1[cH:4][cH:5][cH:22][cH:23][cH:24]1)([O:6][CH2:7][CH2:8][c:9]1[n:10][o:11][c:12](-[c:14]2[c:15]([CH3:21])[n:16][c:17]([Cl:20])[cH:18][cH:19]2)[n:13]1)[c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)([CH3:31])([CH3:32])[CH3:33].[CH3:35][CH2:36][CH2:37][CH2:38][N+:39]([CH2:40][CH2:41][CH2:42][CH3:43])([CH2:44][CH2:45][CH2:46][CH3:47])[CH2:48][CH2:49][CH2:50][CH3:51].[F-:34].[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1>>[OH:6][CH2:7][CH2:8][c:9]1[n:10][o:11][c:12](-[c:14]2[c:15]([CH3:21])[n:16][c:17]([Cl:20])[cH:18][cH:19]2)[n:13]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 595256053-[3-(2-{[tert-Butyl(diphenyl)silyl]oxy}ethyl)-1,2,4-oxadiazol-5-yl]-6-chloro-2-methylpyridine

Product 1

HCID 595258502-[5-(6-Chloro-2-methylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]ethanol

Sources & evidence

ORD record
ord-4accc2a973e54cfeb2f3075a8ebfb576
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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