Dichloromethane → 5-((5-Amino-4-(piperidin-4-ylmethoxy)pyridin-2-yl)amino)pyrazine-2-carbonitrile
Reaction equation
[Cl:39][CH2:40][Cl:41].[NH2:1][c:2]1[c:3]([O:17][CH2:18][CH:19]2[CH2:20][CH2:21][N:22]([C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[CH2:23][CH2:24]2)[cH:4][c:5]([NH:8][c:9]2[n:10][cH:11][c:12]([C:15]#[N:16])[n:13][cH:14]2)[n:6][cH:7]1.[OH:32][C:33]([C:34]([F:35])([F:36])[F:37])=[O:38]>>[NH2:1][c:2]1[c:3]([O:17][CH2:18][CH:19]2[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]2)[cH:4][c:5]([NH:8][c:9]2[n:10][cH:11][c:12]([C:15]#[N:16])[n:13][cH:14]2)[n:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-bf62c29c967346059eed53d8fd296c5e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…