Dimethylformamide → 2-Methyl-5-(4-{[3-(1H-pyrazol-1-yl)phenyl]acetyl}-1-piperazinyl)quinoline
Reaction equation
[CH3:11][c:12]1[n:13][c:14]2[cH:15][cH:16][cH:17][c:18]([N:22]3[CH2:23][CH2:24][N:25]([CH2:28][CH2:29][c:30]4[cH:31][c:32]([NH2:36])[cH:33][cH:34][cH:35]4)[CH2:26][CH2:27]3)[c:19]2[cH:20][cH:21]1.[CH3:52][N:53]([CH3:54])[CH:55]=[O:56].[OH:1][n:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7][cH:8]2)[n:9][n:10]1.[n:37]1(-[c:42]2[cH:43][c:44]([CH2:48][C:49](=[O:50])[OH:51])[cH:45][cH:46][cH:47]2)[n:38][cH:39][cH:40][cH:41]1>>[CH3:11][c:12]1[n:13][c:14]2[cH:15][cH:16][cH:17][c:18]([N:22]3[CH2:23][CH2:24][N:25]([C:49]([CH2:48][c:44]4[cH:43][c:42](-[n:37]5[n:38][cH:39][cH:40][cH:41]5)[cH:47][cH:46][cH:45]4)=[O:51])[CH2:26][CH2:27]3)[c:19]2[cH:20][cH:21]1Participants
5
Sources & evidence
- ORD record
- ord-61bed9a6f51f4f68b6bacca95b103881
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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