Sodium Hydroxide → Sodium benzo[D]oxazole-2-carboxylate

Participants

Reaction Steps

To benzoxazole-2-carboxylic acid ethyl ester (437 mg, 4 mmol) was added 2 mL of THF and 4 mL of NaOH solution (2N in MeOH). The reaction mixture was stirred at room temperature overnight. The suspension was filtered and the solid was dried under vacuum to give 160 mg of benzoxazole-2-carboxylic acid sodium salt as an off-white solid.

Provenance & Evidence