HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 294404Generated: October 30, 2026
1,4-Dioxane → 6-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-N-(2,2,3,3,3-pentafluoro-propyl)-nicotinamide
https://huagongshe.com/reaction/294404
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 2,2,3,3,3-Pentafluoropropylamine | HCID 79002 | — |
| Reactant | Trimethylaluminum | HCID 16682925 | — |
| Reactant | 6-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester | HCID 66718131 | — |
| Product | 6-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-N-(2,2,3,3,3-pentafluoro-propyl)-nicotinamide | HCID 46928666 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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| ORD ID | ord-c362d05e59b5493c9d7cc367eb7817bc |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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