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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 29441Erstellt: 25. Oktober 2026

Sodium Hydroxide → 5-Methyl-benzooxazole-2-carboxylic acid sodium salt

https://huagongshe.com/reaction/29441

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktSodium HydroxideHCID 14798—
Edukt5-Methyl-benzooxazole-2-carboxylic acid ethyl esterHCID 68713060—
LösungsmittelTetrahydrofuranHCID 8028—
Produkt5-Methyl-benzooxazole-2-carboxylic acid sodium saltHCID 68713096—

Reaktionsschritte

To 5-methyl-benzooxazole-2-carboxylic acid ethyl ester (170 mg) was added 2 mL of THF, and 0.83 mL (2 eq) of sodium hydroxide solution (2N in MeOH). The reaction mixture was stirred at room temperature overnight. The suspension was filtered and the solid was dried under vacuum to give 144 mg of 5-methyl-benzooxazole-2-carboxylic acid sodium salt as an off-white solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07420001B2
Quelldatensatzuspto-grants-2008_09
ORD IDord-2bcbbd2cb4ec4104b09d0eac7f1c2258
Quellennotizuspto-grants-2008_09