HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → 5-Methyl-benzooxazole-2-carboxylic acid sodium salt
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | 5-Methyl-benzooxazole-2-carboxylic acid ethyl ester | HCID 68713060 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 5-Methyl-benzooxazole-2-carboxylic acid sodium salt | HCID 68713096 | — |
Reaktionsschritte
To 5-methyl-benzooxazole-2-carboxylic acid ethyl ester (170 mg) was added 2 mL of THF, and 0.83 mL (2 eq) of sodium hydroxide solution (2N in MeOH). The reaction mixture was stirred at room temperature overnight. The suspension was filtered and the solid was dried under vacuum to give 144 mg of 5-methyl-benzooxazole-2-carboxylic acid sodium salt as an off-white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07420001B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-2bcbbd2cb4ec4104b09d0eac7f1c2258 |
| Quellennotiz | uspto-grants-2008_09 |