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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29445Generated: October 26, 2026

Sodium Hydroxide → 857081-42-6

https://huagongshe.com/reaction/29445

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 5-chloro-1,3-benzothiazole-2-carboxylateHCID 63357893—
SolventTetrahydrofuranHCID 8028—
Product857081-42-6HCID 68717138—

Reaction Steps

To 5-chloro-benzothiazole-2-carboxylic acid ethyl ester (200 mg, 0.83 mmol) was added 3 mL of THF, and 0.83 mL (2 eq) of NaOH solution (2N in MeOH). The reaction mixture was stirred at room temperature overnight. The suspension was filtered and the solid was dried under vacuum to give 170 mg of 5-chloro-benzothiazole-2-carboxylic acid sodium salt as an off-white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07420001B2
Source datasetuspto-grants-2008_09
ORD IDord-fc3d1e80ce71433185d60e5556f9662d
Source noteuspto-grants-2008_09