HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 857081-42-6
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 5-chloro-1,3-benzothiazole-2-carboxylate | HCID 63357893 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 857081-42-6 | HCID 68717138 | — |
Reaction Steps
To 5-chloro-benzothiazole-2-carboxylic acid ethyl ester (200 mg, 0.83 mmol) was added 3 mL of THF, and 0.83 mL (2 eq) of NaOH solution (2N in MeOH). The reaction mixture was stirred at room temperature overnight. The suspension was filtered and the solid was dried under vacuum to give 170 mg of 5-chloro-benzothiazole-2-carboxylic acid sodium salt as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07420001B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-fc3d1e80ce71433185d60e5556f9662d |
| Source note | uspto-grants-2008_09 |