Bromide ion → 4-(3-Fluorophenyl)-1-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-ol
Reaction equation
[Br-:1].[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[F:10][C:11]([c:12]1[n:13][n:14][c:15]2[n:16]1[n:17][c:18]([N:21]1[CH2:22][CH2:23][C:24](=[O:27])[CH2:25][CH2:26]1)[cH:19][cH:20]2)([F:28])[F:29].[F:2][c:3]1[cH:4][c:5]([Mg+:9])[cH:6][cH:7][cH:8]1>>[F:2][c:3]1[cH:4][c:5]([C:24]2([OH:27])[CH2:23][CH2:22][N:21]([c:18]3[n:17][n:16]4[c:12]([C:11]([F:10])([F:28])[F:29])[n:13][n:14][c:15]4[cH:20][cH:19]3)[CH2:26][CH2:25]2)[cH:6][cH:7][cH:8]1Participants
5
Sources & evidence
- ORD record
- ord-3d4d225de7c24dfbb2b324d7e4bf1ca0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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