Sodium ion → benzyl N-[1-[2-(hydroxymethyl)-4-[(2-methylpropan-2-yl)oxycarbonylamino]cyclohexyl]-2-oxopyrrolidin-3-yl]carbamate

HRID 294680Notes

Reaction equation

HRID 294680 reaction equation
[BH4-:34].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]1[C:13](=[O:33])[N:14]([CH:17]2[CH:18]3[C:19](=[O:32])[N:20]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH:21]([CH2:22][CH2:23]2)[CH2:24]3)[CH2:15][CH2:16]1.[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[Na+:35].[OH2:41]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]1[C:13](=[O:33])[N:14]([CH:17]2[CH:18]([CH2:19][OH:32])[CH2:24][CH:21]([NH:20][C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:22][CH2:23]2)[CH2:15][CH2:16]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 962WaterHCID 8028TetrahydrofuranHCID 28123BorohydrideHCID 21074906Tert-butyl 7-oxo-2-[2-oxo-3-(phenylmethoxycarbonylamino)pyrrolidin-1-yl]-6-azabicyclo[3.2.1]octane-6-carboxylate

Product 1

HCID 69038514benzyl N-[1-[2-(hydroxymethyl)-4-[(2-methylpropan-2-yl)oxycarbonylamino]cyclohexyl]-2-oxopyrrolidin-3-yl]carbamate

Sources & evidence

ORD record
ord-8657d65a6b6b47ba909c35761bb50237
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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