HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid methylene chloride → 4-Ethoxycarbonylmethoxy-3-methyl-benzofuran-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Reactant | 4-Ethoxycarbonylmethoxy-3-methyl-benzofuran-2-carboxylic acid tert-butyl ester | HCID 68714959 | — |
| Product | 4-Ethoxycarbonylmethoxy-3-methyl-benzofuran-2-carboxylic acid | HCID 68711372 | — |
Reaction Steps
The above 4-ethoxycarbonylmethoxy-3-methyl-benzofuran-2-carboxylic acid tert-butyl ester was dissolved into a 40% TFA/methylene chloride solution, and stirred at room temperature for 4 hours. Evaporation of solvent gave 4-ethoxycarbonylmethoxy-3-methyl-benzofuran-2-carboxylic acid in quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07420001B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-f784bd529321459a945380ab3b571aa5 |
| Source note | uspto-grants-2008_09 |