HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxy-3-methyl-benzofuran-2-carboxylic acid tert-butyl ester → 4-Hydroxy-3-methyl-1-benzofuran-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxy-3-methyl-benzofuran-2-carboxylic acid tert-butyl ester | HCID 13849456 | — |
| Solvent | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Product | 4-Hydroxy-3-methyl-1-benzofuran-2-carboxylic acid | HCID 9497662 | — |
Reaction Steps
4-Hydroxy-3-methyl-benzofuran-2-carboxylic acid tert-butyl ester (Example 156, Step 2) was dissolved in a 40% TFA/methylene chloride solution at room temperature for 4 hours. 4-Hydroxy-3-methyl-benzofuran-2-carboxylic acid was isolated as a white powder by evaporation of the solvent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07420001B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-b2d27b4ac385476d9e797053ae00c82d |
| Source note | uspto-grants-2008_09 |