Sodium ion → 1-(4-fluorophenyl)-4-[5-[(5-methoxy-1H-indol-3-yl)methyl]-3,6-dihydro-2H-pyridin-1-yl]butan-1-ol

HRID 295340Notes

Reaction equation

HRID 295340 reaction equation
[BH4-:1].[CH3:3][O:4][c:5]1[cH:6][c:7]2[c:8]([CH2:14][C:15]3=[CH:20][CH2:19][CH2:18][N:17]([CH2:21][CH2:22][CH2:23][C:24](=[O:25])[c:26]4[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]4)[CH2:16]3)[cH:9][nH:10][c:11]2[cH:12][cH:13]1.[CH:33]([OH:34])([CH3:35])[CH3:36].[Na+:2]>>[CH3:3][O:4][c:5]1[cH:6][c:7]2[c:8]([CH2:14][C:15]3=[CH:20][CH2:19][CH2:18][N:17]([CH2:21][CH2:22][CH2:23][CH:24]([OH:25])[c:26]4[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]4)[CH2:16]3)[cH:9][nH:10][c:11]2[cH:12][cH:13]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 3776IsopropanolHCID 28123BorohydrideHCID 98660505-methoxy-3-[N-(4-(4-fluoro-phenyl)-4-oxo-butyl)-1,2,5,6-tetrahydro-pyridin-3-ylmethyl]-1H-indole

Product 1

HCID 189408151-(4-fluorophenyl)-4-[5-[(5-methoxy-1H-indol-3-yl)methyl]-3,6-dihydro-2H-pyridin-1-yl]butan-1-ol

Sources & evidence

ORD record
ord-1ba7b25f024c4124862a2e4510ecded8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…