HRID29541

反应详情

EQUATION

反应方程式

HRID 29541 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

2

PROCEDURE

实验过程

The title compound was prepared according to the general procedure for the synthesis of heterocyclyl and heteroaryl substituted phenylsulfonyl derivatives previously described, using 4-Bromo-N-[4,5-difluoro-2-(pyridine-3 -carbonyl)-phenyl]-benzenesulfonamide 0.2 g (0.44 mmol), potassium phosphate tribasic monohydrate 0.607 g (2.64 mmol), rac-2,2′-bis (diphenylphosphino)-1,1′-binaphthyl 0.082 g (0.06 mmol), morpholine 0.30 g (2.2 mmol) and Pd (dba)3 0.06 g (0.06 mmol) in 2 ml DMF. HPLC purification gave yellow title compound.

WORKUP

后处理

  1. customThe title compound was prepared
  2. customHPLC purification