Water → 1-(2,2,2-Trifluoroacetyl)indoline-5-carbonitrile

HRID 295492Notes

Reaction equation

HRID 295492 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([C:11]([C:12]([F:13])([F:14])[F:15])=[O:16])[CH2:6][CH2:5]2.[Cu:17][C:18]#[N:19].[O:20]=[CH:21][N:22]([CH3:23])[CH3:24].[OH2:25]>>[c:2]1([C:18]#[N:19])[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([C:11]([C:12]([F:13])([F:14])[F:15])=[O:16])[CH2:6][CH2:5]2

Participants

5

Reactant 4

HCID 962WaterHCID 6228DimethylformamideHCID 86625990Ethanone, 1-(5-bromo-2,3-dihydro-1H-indol-1-yl)-2,2,2-trifluoro-HCID 178418546HCID 178418546, compound

Product 1

HCID 866259911-(2,2,2-Trifluoroacetyl)indoline-5-carbonitrile

Sources & evidence

ORD record
ord-24c3f37e7d284cb8bf344f5db364b05e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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